The C5AR1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The C5AR1 Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Western Blot.
Description
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed: 1847994, PubMed: 8182049, PubMed: 7622471, PubMed: 9553099, PubMed: 10636859, PubMed: 15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed: 8182049, PubMed: 7622471, PubMed: 9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed: 10636859, PubMed: 15153520)